J. Kos, T. Goněc, M. Oravec
Nov 14, 2020
Citations
0
Influential Citations
0
Citations
Journal
Chemistry Proceedings
Abstract
A set of six 3-hydroxynaphthalene-2-carboxanilides, substituted on the anilide ring by combinations of methoxy–methoxy, methoxy–fluoro and methoxy–chloro groups at different positions, was designed. All the molecules were prepared by microwave-assisted synthesis. The compounds were tested for their ability to inhibit photosynthetic electron transport (PET) in spinach (Spinacia oleracea L.) chloroplasts. The PET-inhibiting activity of the compounds was rather moderate. N-(3,5-Dimehoxyphenyl)-3-hydroxynaphthalene-2-carboxamide demonstrated the highest activity (IC50 = 24.5 µM) within the series. These compounds are supposed to inhibit PET in photosystem II.