G. Uddin, A. Latif, M. Arfan
Feb 1, 2013
Citations
0
Influential Citations
7
Citations
Journal
Phytochemistry Letters
Abstract
Abstract Three new phenolic compounds, sorlanin (4-(3-(hydroxymethyl)-5-methoxy-7-phenyl-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)-2-methoxyphenol, 1 ), sorbanin (2-((3,5-dimethoxy-[1,1′-biphenyl]-4-yl)oxy)-1-(4-hydroxy-3-methoxyphenyl)propane-1,3-diol, 2 ) and sorbalanin (4-(3-(hydroxymethyl)-5,6-dimethoxy-2,3-dihydrobenzo[b][1,4]dioxino[2,3-g]benzofuran-2-yl)-2-methoxyphenol, 3 ), together with eight known compounds, polystachyol ( 4 ), isolariciresinol ( 5 ), dihydrodehydrodiconiferyl alcohol ( 6 ), tuberculatin ( 7 ), ovafolinin E ( 8 ), aucuparin ( 9 ), 2′-methoxyaucuparin ( 10 ), and tetracosyl-3-(3,4-dihydroxyphenyl)acrylate ( 11 ), were isolated from Sorbus lanata . The structures of these phytoconstituents were elucidated through extensive spectroscopic techniques, including UV, IR, 1D and 2D NMR, ESI-MS and HRESI-MS experiments. All the compounds except 9 and 10 were isolated for the first time from the genus Sorbus . The isolated compounds were also tested in DPPH radical scavenging reaction where compounds 6 , 7 , 10 and 11 showed significant activities with IC 50 values of 9.2, 11.7, 23.0 and 33.7 μM, respectively.