S. El-Desouky, S. Ryu, Young-Kyoon Kim
Jun 4, 2007
Citations
0
Influential Citations
20
Citations
Quality indicators
Journal
Tetrahedron Letters
Abstract
Abstract A novel alkylated piperazine (3α,5α-diisobutyryl-6α-isopropyl-piperazine-2-one, 1 ) has been isolated from the n -butanol soluble part of the leaves extract of Arum palaestinum Boiss., the chemical structure and the relative stereochemistry of 1 were elucidated on the basis of 1D and 2D NMR spectroscopic data. Piperazirum showed a significant cytotoxicity against cultured tumor cell lines in vitro.