K. Wadhwa, J. Verkade
Jul 29, 2009
Citations
0
Influential Citations
11
Citations
Journal
Tetrahedron Letters
Abstract
Abstract Herein we report the use of commercially available P( i -PrNCH 2 CH 2 ) 3 N ( 1a ) as an efficient catalyst for 2-trimethylsilyl-1,3-dithiane (TMS–dithiane) addition to aldehydes at room temperature. The catalyst loading required for these reactions (5 mol %) is the lowest recorded in the literature, and the majority of the reaction times for this transformation are the shortest thus far reported. A variety of functional groups are tolerated on the aryl aldehyde substrates.