M. McFerren
Apr 1, 2006
Citations
0
Influential Citations
13
Citations
Journal
Journal of the American Academy of Dermatology
Abstract
Plants have and continue to provide medicine with an abundance of pharmacologically interesting and useful chemicals. In recent years, cyclopamine, a steroidal alkaloid isolated from Veratrum californicum, has been instrumental in dissecting the sonic hedgehog pathway. This brief report outlines cyclopamine's discovery with discussion of its potential application to clinical dermatology.