G. Cullberg, Per-Arne Dovré, G. Lindstedt
Jan 1, 1982
Citations
0
Influential Citations
50
Citations
Quality indicators
Journal
Acta Obstetricia et Gynecologica Scandinavica
Abstract
Abstract. Ethinylestradiol (EE, 17α‐ethynyl‐1,3,5(10)‐es‐tratriene‐3,17β‐diol) 30 μg daily, in combination with 150μg per day of desogestrel (Org 2969,17α‐ethynyl‐18‐methyl‐11‐methylene‐4‐estrene‐17β‐ol) or levonorgestrel (17α‐ethynyl‐18‐methyl‐4‐estrene‐17β‐ol‐3‐one), was administered to two groups of 10 healthy human women who had been without hormonal treatment during 3 months prior to the study. The preparations were given for three 21‐day cycles with 7‐day intervals. Blood samples were taken before treatment and at the end of the third treatment period. Serum sex‐hormone binding globulin (SHBG), ceruloplasmin, ornsomucoid, C1‐esterase inhibitor and C4 were analyzed by electroimmunoassay and transcortin was assayed as cortisol‐binding capacity. Serum testosterone was assayed by radioimmunoassay of methylenedichloride extracts using an antiserum with about 20% cross‐reactivity for dihydrotestosterone (DHT).