P. Braquet
1997
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Abstract
Platelet-activating factor (PAF), a potent phospholipid inflammatory mediator, has been implicated in several pathophysiological disorders. The discovery of selective PAF receptor antagonists has greatly facilitated the accumulation of knowledge on the role of PAF in animal models of these disorders (see, for reviews, [1–3]). The use of selective, potent, orally active PAF receptor antagonists may, at least in part, allow us to successfully explore the problematic points of PAF research.