Taejung Kim, Jung Ho Song, K. Jeong
Jul 1, 2013
Citations
0
Influential Citations
11
Citations
Journal
European Journal of Organic Chemistry
Abstract
A novel series of 1,4-disubstituted 1,2,3-triazole-containing potassium trifluoroborates were prepared in good to excellent yields from the corresponding organohalides and potassium ethynyltrifluoroborate through a regioselective one-pot Cu-catalyzed azide–alkyne cycloaddition (CuAAC) reaction. Further Suzuki–Miyaura cross-coupling of these (organo-1,2,3-triazol-4-yl)trifluoroborates with aryl and alkenyl bromides by using a PdCl2(dppf)·CH2Cl2/TBAB [dppf = 1,1′-bis(diphenylphosphanyl)ferrocene, TBAB = tetrabutylammonium bromide] system under microwave irradiation was explored.