D. Roman, Yoko Takahashi, A. Charette
May 13, 2011
Citations
0
Influential Citations
146
Citations
Quality indicators
Journal
Organic letters
Abstract
Potassium tert-butoxide mediated intramolecular cyclization of aryl ethers, amines, and amides was efficiently performed under microwave irradiation to provide the corresponding products in high regioisomeric ratios. The reaction proceeds via single-electron transfer to initiate the formation of an aryl radical, followed by a kinetically favored 5-exo-trig and subsequent ring expansion.