Brent A. Banasik
Jan 31, 2017
Citations
0
Influential Citations
2
Citations
Journal
Journal name not available for this finding
Abstract
A simple and efficient method for the synthesis of biotin pre-functionalized linkers via orthogonal protecting group elongation strategy is reported for a single-step preparation of new biosensor probes. The target compound 4(4(4(5((3S, 4S, 6R)-2-oxohexahydro-1H-thieno[3,4]imidazol-4-yl) pentanamido) butanamido) butanamido) butanoic acid (5) was synthesized in five linear steps with a 40% overall yield.