A. Myers, M. Alauddin, M. Fuhry
1989
Citations
0
Influential Citations
38
Citations
Journal
Tetrahedron Letters
Abstract
Abstract (Z)-Ethyl 2,3-dibromopropenoate, readily available in multigram quantities, undergoes selective replacement of the β-bromide in coupling reactions with trimethylsilylacetylene to produce the (Z)-enyne 2. This product may be further elaborated to various functionalized enynes of defined geometry or may be coupled with a second acetylenic reactant to produce (Z)-enediynes.