Hailiang Liao, Aimin Li, Xingsong Chen
Jul 7, 2016
Citations
0
Influential Citations
3
Citations
Journal
Synlett
Abstract
Abstract A batchwise, multigram preparation of 2-azabicyclo-[2.1.1]hexane hydrochloride (1·HCl) was developed, delivering a total of 195 grams of material. The key synthetic step involves an intramolecular displacement of a primary alkyl chloride with a tert-butylsulfinamide to forge the [2.1.1]-bicyclic ring system.