J. Gonzalez-Gomez, E. Uriarte
Nov 1, 2003
Citations
0
Influential Citations
9
Citations
Journal
Synlett
Abstract
An efficient synthesis of 2-chloro-6-methoxypyridazino[4,3-h]psoralen was achieved by Diels-Alder reaction of 3,6-dichloro-1,2,4,5-tetrazine and 8-methoxy-psoralen (8-MOP) in a one-pot procedure. The convenient transformation of this intermediate into the 2-triflate derivative allowed efficient palladium-catalyzed reduction, methoxycarbonylation, and Sonogashira cross-coupling reactions at C 2 .