L. Xiang
2006
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Journal
Chinese Journal of Pharmaceuticals
Abstract
3-Dimethylamino-3-phenylpropanol was prepared from benzaldehyde and malonic acid by Knoevenagel reaction and reduction with NaBH4-I2 system to give 3-amino-3-phenylpropanol followed by Eschweiler-Clark reaction with an overall yield of 29% based on benzaldehyde.