W. Todd, B. K. Carpenter, R. Schwarcz
1989
Citations
0
Influential Citations
27
Citations
Journal
Preparative biochemistry
Abstract
The chemical syntheses of 4-fluoro-, 4-chloro-, and 4-bromo-3-hydroxyanthranilic acids are described. Their actions as inhibitors of 3-hydroxyanthranilate oxygenase in cell-free homogenates from rat and human brain and in rat brain slices are presented.