Tomonobu Ishida, S. Kikuchi, T. Yamada
Jul 2, 2013
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Influential Citations
82
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Quality indicators
Journal
Organic letters
Abstract
Although 4-hydroxyquinolin-2(1H)-one derivatives have attracted much attention due to their biological benefits, conventional reactions under harsh heat conditions must be employed to provide these key compounds. In the presence of a catalytic amount of silver salt, various o-alkynylanilines were treated with carbon dioxide and a base under mild reaction conditions to afford the corresponding 4-hydroxyquinolin-2(1H)-one derivatives in high yield.