G. Hartman, W. Halczenko, J. D. Prugh
Mar 1, 1990
Citations
0
Influential Citations
4
Citations
Journal
Journal of Heterocyclic Chemistry
Abstract
An efficient synthetic route is reported for the preparation of thieno[2,3-e]furan-2-sulfonamides bearing oxygenated functionality at C-5. The method employs conversion of furan-3-carboxaldehyde to an intermediate that, in the key step, undergoes facile cyclodehydration to the fused [5,5] heterocycle under mild Knoevenagel conditions.