Renhei Liu, Min Zhang, Thomas P. Wyche
Jul 23, 2012
Citations
0
Influential Citations
43
Citations
Journal
Angewandte Chemie
Abstract
A general strategy was developed for the diastereo- and enantioselective synthesis of cyclobutanes with four different substituents. It consists of three transition metal-catalyzed reactions — a RhII-catalyzed cyclopropanation, a AgI-catalyzed regioselective and stereospecific ring expansion, and a RhI-catalyzed addition reaction. Structures of pipercyclobutanamide A and piperchabamide G were synthesized and revised.