Jun Luo, En-Jian Han, Qian Shen
Nov 10, 2016
Citations
0
Influential Citations
8
Citations
Journal
Organic Process Research & Development
Abstract
Cu-promoted reactions of 1,1-dichloro-2,2,2-trifluoroethane (HCFC-123) with dialkyl phosphonates produced dialkyl (2,2,2-trifluoroethyl)phosphonates efficiently under mild conditions by successively activating the two inert C–Cl bonds in HCFC-123. These reactions can be efficiently carried out on a >30 g scale with moderate to good yields.