C. Birk, J. Voss, J. Wirsching
Nov 28, 1997
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0
Influential Citations
17
Citations
Journal
Carbohydrate Research
Abstract
Abstract Benzyl 2- deoxy-3,5-di -O- methyl-1,4-dithio- l -threo- pentofuranoside (5) is synthesized in five steps starting with 2-deoxy- d -ribose. The anomers 5α and 5β are separated and their configuration is unequivocally assigned by use of NOE measurements. 2- Deoxy-3,5-di -O- methyl-4-thio- l -threo- pentofuranose is obtained from 5 and mercuric 4-nitrobenzoate. The corresponding nucleosides are prepared from 5 and bis-(trimethylsilyl)uracil or bis-(trimethylsilyl)thymine in the presence of N -iodosuccinimide.