H. W. Pinnick, Michael A. Reynolds
1979
Citations
0
Influential Citations
7
Citations
Journal
Synthetic Communications
Abstract
Abstract We report a convenient synthesis of ethyl hypophosphite by the O-alkylation of sodium hypophosphite (eq 1). Thus, when sodium hypo-phosphite is allowed to react with triethyloxonium tetrafluoroborate in methylene chloride at 0°, simple filtration from the inorganic salts and evaporation of the solvent gives the pure ester in 80% yield. This simple preparation employs readily available starting materials3.