L. Antal, G. Dombi, C. Novak
1996
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Abstract
Tolperisone HCl (T) is an original Hungarian drug molecule. It is well soluble in water [1]. From a scientific aspect, it may be very interesting to investigate how a compound that is readily soluble in water forms inclusion complexes with cyclodextrins (CDs) [2]. The aim was to study the conditions of complex formation with different Cds, such as α-CD, β-CD, γ-CD, DIMEB and RAMEB, by using various preparation technniques and investigation methods.