A. Zanka, A. Takeuchi, A. Kubota
Jun 16, 1998
Citations
0
Influential Citations
27
Citations
Journal
Organic Process Research & Development
Abstract
Large-scale monochlorination of 4-aminoacetophenone using iodobenzene dichloride is described. Special emphasis was given to the characterization of the iodobenzene dichloride and to the development of a practical procedure for handling this agent from the viewpoint of hazards. This process was successfully scaled up in a pilot plant.