J. Klose, C. Reese, Q. Song
Oct 20, 1997
Citations
0
Influential Citations
39
Citations
Journal
Tetrahedron
Abstract
Abstract The title compound 3 and 4-[(2-cyanoethyl)sulfanyl]morpholine-3,5-dione 12 are both conveniently prepared in good yield from 2-cyanoethyl disulfide, which itself is readily prepared in one step from S -(2-cyanoethyl)isothiouronium chloride 4 . In the same way, dimethyl and diphenyl disulfides are converted into 2-methylsulfanyl- and 2-phenylsulfanyl-1 H -isoindole-1,3-(2 H )-diones 8a and 8b , respectively, also in good yields.