Jiang Neng-qiao
2011
Citations
0
Influential Citations
0
Citations
Journal
Fine Chemical Intermediates
Abstract
(-)-(6S)2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole,an important chiral intermediate for Pramipexole which is a non-ergoline dopamine agonist,was prepared from 2-amino-6-acetamido-4,5,6,7-tetrahydrobenzothiazole hydrobromide and resolved with L(+)tartaric acid.The title compound was obtained in an overall yield of 75% and its structure was confirmed with 1H NMR and IR.