T. Kikukawa, Y. Iizuka, T. Sugimura
Jul 5, 1987
Citations
0
Influential Citations
13
Citations
Journal
Chemistry Letters
Abstract
Optically pure (R)- and (S)-3-hydroxybutanoic acid and its homologues are prepared by the method consisting of the enantioface differentiating hydrogenation of methyl 3-oxoalkanoate to methyl 3-hydroxyalkanoate(80–90% e.e.) over asymmetrically modified nickel catalyst and the preferential crystallization of optically pure 3-hydroxyalkanoic acids from the hydrogenation products as the dibenzylammonium salts.