T. Sugimura, M. Yoshikawa, Tohru Yoneda
Apr 1, 1990
Citations
0
Influential Citations
11
Citations
Journal
Bulletin of the Chemical Society of Japan
Abstract
Optically pure 2,6-dimethyl-3,5-heptanediol (1), a new chiral auxiliary, has been prepared by the enantiodifferentiating hydrogenation of 2,6-dimethyl-3,5-heptanedione over tartaric acid–NaBr–modified Raney nickel catalyst (TA–NaBr–MRNi), and the preferential recrystallization of the hydrogenation product. Absolute configuration of 1 was determined to be 3S, 5S by the chemical correlation with (−)-ethyl (S)-3-hydroxy-4-methylpentanoate.