T. Razzaq, C. Kappe
Apr 2, 2007
Citations
0
Influential Citations
27
Citations
Journal
Tetrahedron Letters
Abstract
Abstract 4-Hydroxy-6-methyl-2 H -pyrano[3,2- c ]quinoline-2,5(6 H )-dione was prepared by microwave-assisted cyclocondensation of N -methylaniline with 2 equiv of diethyl malonate. Key to the success of the synthesis was the use of open vessel controlled microwave heating technology, allowing the simultaneous removal of the formed ethanol from the reaction mixture by fractional distillation.