Rajasekhar Reddy Naredla, B. P. Dash, D. Klumpp
Sep 9, 2013
Citations
0
Influential Citations
13
Citations
Journal
Organic letters
Abstract
In the reactions of 2,3-pyrazinedicarboxylic anhydride with amines and anilines, pyrazine carboxamides are formed in good to excellent yields. A mechanism is proposed involving ring opening of the anhydride and decarboxylation of the heterocyclic ring. Based on other similar heterocyclic decarboxylations, this suggests the involvement of an N-heterocyclic carbene intermediate leading to the product.