Yang Jing-jing
2008
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Journal
Strait Pharmaceutical Journal
Abstract
OBJECTIVE To prepare tetrahydrozoline hydrochloride nasal solution and establish its quality control method.METHODS Tetrahydrozoline hydrochloride nasal solution was prepared.The content of tetrahydrozoline hydrochloride in the nasal solution was determined by HPLC.RESULTS Using 237 nm as detecting wavelength,the regression equation was Y=13313.86X+1.6006,r=99995,and the linear range was 20.0~60.0μg· mL-1 with the average recovery 99.8%,RSD was 0.437%(n=6).CONCLUSIONS The preparation process of tetrahydrozoline hydrochloride nasal solution is simple and stable and the quality is easy to control.