A. E. Rashad, H. Sayed, A. Shamroukh
Dec 1, 2005
Citations
0
Influential Citations
30
Citations
Journal
Phosphorus, Sulfur, and Silicon and the Related Elements
Abstract
Compounds 2 and 9 were formed using 3-(4-chloro-phenyl)-1-pyridin-2-yl propenone ( 1 ) and malononitrile or ethyl cyanoacetate, respectively. The pyridine derivative 2 was in turn used as a precursor for the preparation of some pyridopyrimidine and fused pyridopyrimidine derivatives 3–8 On the other hand, the pyridine derivative 9 was used for the preparation of thienopyridine derivatives 11 and 12 Nitrozation of compound 12 afforded pyridothienotriazine derivative 13 Some of the prepared products showed potent antimicrobial activity.