D. Chadwick, J. Chambers, H. Hargraves
1973
Citations
0
Influential Citations
21
Citations
Journal
Journal of The Chemical Society-perkin Transactions 1
Abstract
A series of heterocyclic 2-carbaldehydes and 2-[2H]carbaldehydes have been prepared, most of them by Vilsmeier formylation of mono- and di-substituted furans and thiophens. Isopropylation of methyl furan-2-carboxylate was used to obtain the 4- and 5-monoisopropyl- and 4,5-di-isopropyl-furan-2-carboxylic acids. With different aryl 2-furyl ketones bromine may attack either the benzenoid ring or the heterocyclic ring preferentially.