Lixiao Wang, X. Wang, Jingnan Cui
Apr 21, 2010
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Influential Citations
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Journal
Tetrahedron-asymmetry
Abstract
Abstract A series of trans-5-substituted-acenaphthene-1,2-diols were obtained in 21–72% yield with 97–100% ee by baker’s yeast-mediated reduction of the corresponding acenaphthylene-1,2-diones, in the presence of DMSO as a co-solvent and under vigorous agitation. The absolute configuration of (−)-trans-5-methoxy-acenaphthene-1,2-diol trans-3b and (−)-trans-5-bromo-acenaphthene-1,2-diol trans-3c was assigned as (S,S) and (−)-trans-5-thiomorpholin-acenaphthene-1,2-diol trans-3d was established as (R,R) by exciton-coupled circular dichroism.