R. Kwok
Aug 1, 1978
Citations
0
Influential Citations
8
Citations
Journal
Journal of Heterocyclic Chemistry
Abstract
The preparation of a number of tricyclic fused ring iminopyrido[3,2-e]pyrimidines is described. Treatment of 2-chloronicotinonitrile with primary amines afforded the corresponding 2-amino derivative which was condensed with ethylenediamine or higher congeners to give substituted cyclic amidines. The latter on treatment with cyanogen bromide gave the desired imino-pyrido[3,2-e]pyrimidines. The preparation of diaminopyrido[2,3-d]pyrimidines and tricyclic quinazolines by related procedures is discussed.