L. Gawell, H. Hall, C. Köhler
Oct 1, 1985
Citations
0
Influential Citations
11
Citations
Journal
Journal of Labelled Compounds and Radiopharmaceuticals
Abstract
A method for the preparation of tritium labelled potential neuroleptics of the benzamide class possessing highly potent dopamine- D2 binding properties, is described. The pyrrolidine moiety of the molecule is labelled with tritium by hydrogenation, to a specific activity of up to 58 Ci/mmol and subsequently reacted with an acid chloride. The specificity of the label is confirmed by 3H-NMR.