A. Yavolovskii, É. I. Ivanov
2007
Citations
0
Influential Citations
2
Citations
Journal
Russian Journal of General Chemistry
Abstract
We have found that 6-amino-5-nitrosouracil (I) reacts with semicarbazides to give hexahydropyrimido[5,4-e][1,2,4]triazine-3,5,7-trione 4-oxide (II). Complete conversion of nitrosouracil I in a mixture of semicarbazide hydrochloroide and sodium acetate in aqueous solution at 60 65 C is attained in 1 h. Treatment of triazine N-oxide II with a hot solution of ammonia leads to the formation of 3-amino derivative III.