Hong Shu, Yan Wang, Puqin Cai
Jul 1, 2007
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Journal
Chinese Chemical Letters
Abstract
Abstract A novel one-pot synthetic method of 4-methylimidazol-2-one is described. The target compound is conveniently synthesized from sodium diformylamide, a modified Gabriel reagent prepared, through condensation, hydrolyzation and cyclization reactions without separating intermediates, its total yield is 75.8%.