K. Tserng, D. Hachey, P. Klein
May 1, 1977
Citations
3
Influential Citations
182
Citations
Quality indicators
Journal
Journal of lipid research
Abstract
Glycine and taurine conjugates of 5beta-cholanic acids have been synthesized using improved procedures based on the peptide coupling reagent, N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline. The conjugates are obtained in chromatographically pure form in yields higher than 90%. The use of this procedure in the large scale preparation of cholyl[1,2-13C2]glycine is described.