Deguang Zhu, Ruijiao Chen, Haibo Liang
Apr 1, 2010
Citations
0
Influential Citations
3
Citations
Journal
ChemInform
Abstract
A series of 5-substituted morpholin-2-one-3-carbox-amide derivatives were efficiently synthesized by a Ugi three-component reaction involving chiral 5,6-dihydro[1,4]oxazin-2-one substrates, isocyanides and carboxylic acids. The newly formed chiral center in the product was obtained in good diastereoselectivity.