By M. Z. E. A. Awad, R. Mcdowall
2006
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Journal
The Journal of Physiology
Abstract
The action of mersalyl on the 'sodium pump '. By M. Z. E. A. AWAD and R. J. S. MCDOWALL. Department ofPhysiology, King's College, London Mersalyl is used to promote the excretion of sodium chloride and water by the kidney, it is believed, by reducing tubular reabsorption. Minute doses do not apparently affect the isolated rat diaphragm in the Krebs solution, but they render it abnnormally sensitive to the effects of anoxia. The failure of the preparation produced by the mersalyl and anoxia is relieved by reducing the sodium chloride in the Krebs solution.