Mao Duo
2000
Citations
0
Influential Citations
0
Citations
Journal
Fine chemicals
Abstract
The 4 amino N [3 (2 hydroxyethyl)sulfonyl]phenylbenzamide was synthesized from 3 (2 hydroxyethyl)sulfonylaniline and 4 nitrobenzoyl chloride by acylation and catalytic hydrogenation,the yields of which were 90.3% and 95.6% respectively ,and the total yield was 86.3%.Using Ranney Ni as catalyst at 0.24 MPa(H\-2),the optimum conditions of catalytic hydrogenation were determined:solvent CH\-3OH,amount of catalyst 30% and reaction temperature 50-60 ℃.The products were confirmed by TLC,IR, 1HNMR and MS.