Caijiao Wu, Qifan Zhou, Dake Song
Sep 6, 2019
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0
Influential Citations
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Journal
Journal of Chemical Research
Abstract
A practical synthetic route to pimavanserin tartrate, in which the target compound was obtained with 99.84% purity and in 46% total yield via a 5-step synthesis starting from 4-hydroxybenzaldehyde and (4-fluorophenyl)methanamine, is reported. The main advantages of the route include inexpensive starting materials, mild reaction conditions and an acceptable overall yield.