G. Welmaker, Joan E. Sabalski
Jun 14, 2004
Citations
0
Influential Citations
22
Citations
Journal
Tetrahedron Letters
Abstract
Abstract A synthesis of 1,2,3,4,8,9,10,10a-octahydro-7b H -cyclopenta[ b ][1,4]diazepino[6,7,1- hi ]indole is described exemplifying a new synthetic route to medicinally interesting compounds. The key step involves a cyclization of 2-(2,3,3a,8b-tetrahydrocyclopenta[ b ]indol-4(1 H )-yl)-ethanamine with aqueous formaldehyde in the presence of trifluoroacetic acid.