Jiang Da-feng
2010
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Journal
Chemical Reagents
Abstract
The process for synthesis of 1-acetyl-4-(4-hydroxyphenyl) piperazine,which was prepared via chlorination,cyclization and acylation of bis-(2-chloroethyl)amine hydrochloride and p-aminophenol,was studied,and the yield of target product reached up to 37.5%.The product was identified by IR spectrometry and 1HNMR spectroscopy.The yield of product obtained by this process is better than that of currently available process,and the process is simple and low in cost.