B. Yang, Miriam E. Goldsmith, J. Rizzi
May 9, 1994
Citations
1
Influential Citations
19
Citations
Journal
Tetrahedron Letters
Abstract
Abstract Beckmann rearrangement of erythromycin A 9(E)-oxime with toluenesulfonyl chloride in ethyl ether at −45°C generates 9,11-imino ether IV which leads to azithromycin. The 9,11-imino ether can also be readily obtained from isomerization of its isomer 6,9-imino ether III .