B. Wipf, E. Kupfer, Roberto Bertazzi
Mar 16, 1983
Citations
1
Influential Citations
140
Citations
Quality indicators
Journal
Helvetica Chimica Acta
Abstract
The production of (S)-ethyl 3-hydroxybutyrate (2) from ethyl acetoacetate (1) in higher yields and with higher optical purity than with the usual procedures was achieved by continuous addition of the substrate 1 and sucrose to an aerated suspension of bakers' yeast. The microbial reduction of 1 by the fungus Geotrichum candidumLINK yields - for the first time - the antipode 3.