P.Praveen kumar, B.Mou nika, D.Sarva mangala
Mar 25, 2017
Citations
1
Influential Citations
4
Citations
Journal
international journal of engineering trends and technology
Abstract
Aspartic acid abbreviated as ASP or D; is encoded by the codons GAU AND GAC also known as aspartate is an alpha amino acid obtained as a product of the hydrolysis of proteins.Aspartic acid was first discovered in 1827 by AUGUSTE-ARTHUR PLISSON and isolated in 1868 from legumin in plant seeds and from asparagus juice. Aspartic acid is not an essential amino acid, which means that it can be synthesized from central metabolic pathway in humans (i.e;) they can synthesize it from oxaloacetic acid formed in the metabolism of carbohydrates and do not require dietary sources. There are two forms or enantiomers of aspartic acid. The name aspartic acid can refer to either enantiomer or a mixture of two. Of these two forms only one L-aspartic acid, is directly incorporated in to proteins. The biological roles of its counterpart, D-aspartic acid are more limited. Most chemical synthesis will produce both forms, DLaspartic acid known as a racemicmixture. It can also be generated from ornithine and citruline in the urea cycle. Aspartate also participates in gluconeogenesis. Aspartic acid acts as a hydrogen acceptor in a chain of ATP synthase system. 2