H. Selye, C. E. Hall
Mar 1, 1944
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Influential Citations
31
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Journal
American Heart Journal
Abstract
Abstract Experiments on albino rats indicate that, if the sodium chloride intake is kept high, desoxycorticosterone acetate regularly produces nephrosclerosis, cast formation in the renal tubules, and hypertrophy of the renal arterioles, as well as marked cardiac hypertrophy. The significance of these observations is discussed in connection with their possible bearing on the cause of nephrosclerosis and hypertensive heart disease in man.