Said Jamal Aboulhoda, Françoise Hénin, Jacques Muzart
1994
Citations
0
Influential Citations
33
Citations
Journal
Tetrahedron-asymmetry
Abstract
Abstract 2-Methyl-1-indanone and 2-methyl-1-tetralone have been obtained with enantiomeric excesses of up to 52% from the corresponding benzyl and allyl β-ketoesters by a multistep reaction: palladium-catalyzed cleavage / decarboxylation / chiral aminoalcohol-mediated enantioselective protonation. The success of the process and particularly of the first step can be very dependent on the nature of the palladium catalyst used.