H. Ludwig, G. Spiteller, D. Matthaei
Nov 1, 1978
Citations
0
Influential Citations
13
Citations
Journal
Journal of Chromatography B: Biomedical Sciences and Applications
Abstract
Abstract Profiles in chronic diseases. I. Investigations of steroid profiles in uremia Steroid profiles of hemofiltrates of uremic patients contain as main steroids the sulfates of 11β-hydroxyetiocholanolone, 11-ketoetiocholanolone, 11β-hydroxyandrosterone and 11-ketoandrosterone. In blood of uremic patients androstenediol is the main steroid fo the sulfate fraction, while in blood of healthy persons dehydroepiandrosterone sulfate is the main steroid. The gradual decrease of the kidney function is characterized by an increase of 11-oxigenated androstane conjugates in urine.